Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626302 | 1.00 | GRM8 (0.48) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL1713768 | 0.84 | CYP1A2 (0.50) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL1713767 | 0.84 | CYP1A2 (0.50) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL2801195 | 0.82 | CYP1A2 (0.48) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL30297672 | 0.82 | CYP1A2 (0.48) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL3249711 | 0.81 | PTGS1 (0.41) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL10636405 | 0.81 | GRM8 (0.47) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL9759339 | 0.79 | CYP1A2 (0.46) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL3785917 | 0.79 | CYP1A2 (0.46) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Hydrochloric Acid SCHEMBL10636188 | 0.79 | GRM8 (0.46) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991016067-A1 | SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-31 | — | — | WO | claimed |
| US-8883229-B2 | Pesticidal compositions and related methods | VALENCIA JOSÉ LUIS MIRANDA (MX) | 2014-11-11 | — | — | US | disclosed |
| US-20130011495-A1 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS- (FR) | 2013-01-10 | — | — | US | disclosed |
| EP-2453745-A2 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | Centre National de la Recherche Scientifique (FR) | 2012-05-23 | — | — | EP | disclosed |
| US-20120040032-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | MIRANDA VALENCIA JOSE LUIS (MX) | 2012-02-16 | — | — | US | disclosed |
| WO-2011007104-A2 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-01-20 | — | — | WO | disclosed |
| EP-0931163-A4 | ASSESSMENT OF INTRACELLULAR CYSTEINE AND GLUTATHIONE CONCENTRATIONS | RES DEV FOUNDATION (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-0931163-A1 | ASSESSMENT OF INTRACELLULAR CYSTEINE AND GLUTATHIONE CONCENTRATIONS | RESEARCH DEVELOPMENT FOUNDATION (US) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998010092-A1 | ASSESSMENT OF INTRACELLULAR CYSTEINE AND GLUTATHIONE CONCENTRATIONS | RESEARCH DEVELOPMENT FOUNDATION (US) | 1998-03-12 | — | — | WO | disclosed |
| WO-1991016067-A1 | SOLUBLE AND STABLE SOURCES OF TYROSINE, CYSTEINE AND GLUTAMINE FOR TOTAL PARENTERAL NUTRITION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040032-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | NOTUM, BPHL, ACHE | GRM8 669/4885GRM6 470/4885GRIN2D 2894/4885 |
| US-20130011495-A1 | ANTIFUNGAL COMPOUNDS AND USE THEREOF | SCLY, SUCLG1, ACSL3 | GRM8 3970/4885GRM6 3919/4885GRIN2D 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.