Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 7/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258463 | 0.85 | — | — | |
| SCHEMBL6257799 | 0.71 | TDP1 (0.34) | SLC6A3FBP1 | |
| SCHEMBL30036876 | 0.69 | SLC6A3 (0.36) | SLC6A3OPRM1 | |
| SCHEMBL6263275 | 0.66 | APLNR (0.34) | FBP1 | |
| SCHEMBL5898085 | 0.63 | — | — | |
| SCHEMBL3257324 | 0.63 | — | — | |
| SCHEMBL2819116 | 0.62 | LAP3 (0.53) | SLC6A3 | |
| SCHEMBL27970992 | 0.61 | SLC6A3 (0.41) | SLC6A3OPRM1 | |
| SCHEMBL26334851 | 0.61 | VHL (0.42) | SLC6A3OPRM1 | |
| SCHEMBL115387 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080406-A2 | COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2005-09-01 | — | — | WO | disclosed |