Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 7/20 | 1.00 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | S100A4 | P26447 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420048 | 0.80 | PTPRC (0.66) | PTPRCNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL4152879 | 0.77 | PTPRC (0.61) | PTPRCNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL29790425 | 0.76 | ACE2 (0.62) | PTPRCCTSLPTPN1CTSSPTPN13 | |
| SCHEMBL15490697 | 0.76 | ACE2 (0.62) | PTPRCCTSLPTPN1CTSSPTPN13 | |
| SCHEMBL6263718 | 0.74 | MAOA (0.90) | PTPRCCTSLPTPN1CTSSPTPN13 | |
| SCHEMBL6262610 | 0.74 | PTPRC (0.73) | PTPRCCTSLPTPN1CTSSPTPN13 | |
| SCHEMBL6259668 | 0.73 | PTPRC (1.00) | PTPRCCTSLPTPN1CTSSPTPN13 | |
| SCHEMBL8528763 | 0.73 | ACE2 (1.00) | PTPRCCTSLPTPN1CTSSPTPN13 | |
| SCHEMBL30519331 | 0.73 | ACE2 (1.00) | PTPRCCTSLPTPN1CTSSPTPN13 | |
| SCHEMBL6259082 | 0.73 | PTPRC (0.95) | PTPRCCTSLPTPN1CTSSPTPN13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242363-B1 | CD45 INHIBITORS | ASTRAZENECA AB (SE) | 2005-11-02 | — | — | EP | disclosed |
| US-20030207812-A1 | Cd45 inhibitors | ASTRAZENECA AB (SE) | 2003-11-06 | — | — | US | disclosed |
| EP-1242363-A2 | CD45 INHIBITORS | AstraZeneca AB (SE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046125-A2 | CD45 INHIBITORS | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207812-A1 | Cd45 inhibitors | CD74, CD2, PTPRC | PTPRC 3/4885CTSL 2041/4885PTPN1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.