SCHEMBL626330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14893921	0.87	TRPV3 (0.46)	TRPV3NPSR1POLBMAPTNR1I2
	SCHEMBL625818	0.85	TRPV3 (0.43)	TRPV3POLBALDH1A1SLC6A2SLC6A4
	SCHEMBL626095	0.83	TRPV3 (0.46)	TRPV3POLBALDH1A1SLC6A2SLC6A4
	SCHEMBL14895928	0.83	TRPV3 (0.48)	TRPV3SLC6A2SLC6A4NR1I2OPRM1
	SCHEMBL626384	0.79	TRPV3 (0.43)	TRPV3ALDH1A1NR1I2OPRK1
	SCHEMBL625314	0.77	TRPV3 (0.61)	TRPV3NPSR1POLBMAPTSLC6A2
	SCHEMBL625133	0.76	TRPV3 (0.48)	TRPV3NPSR1POLBL3MBTL1SLC6A2
	SCHEMBL625556	0.75	TRPV3 (0.43)	TRPV3ALDH1A1SLC6A2SLC6A4NR1I2
	SCHEMBL625770	0.75	TRPV3 (0.43)	TRPV3ALDH1A1NR1I2
	SCHEMBL624617	0.75	TLR7 (0.46)	NPSR1ALDH1A1L3MBTL1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.