Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906080 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL9862039 | 0.91 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| Ridinilazole SCHEMBL29379856 | 0.91 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| Ridinilazole SCHEMBL413723 | 0.91 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL30343722 | 0.89 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL15569849 | 0.89 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL14834116 | 0.87 | KDM4E (0.54) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL417825 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| Ridinilazole SCHEMBL17867397 | 0.84 | NPC1 (0.65) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL419961 | 0.84 | MEN1 (0.77) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030206-A1 | ARYL-1,3-AZOLE DERIVATIVES AND METHODS FOR INHIBITING HEPARNASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |