Urea

Urea

SCHEMBL6264282

C=C.NC(N)=O.NC(N)=S

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
TSHR P16473 4/20 0.55
LMNA P02545 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
ATM Q13315 1/20 0.55
ATR Q13535 1/20 0.55
OR51E2 Q9H255 1/20 0.55
ACHE P22303 1/20 0.39
FGFR4 P22455 1/20 0.38
BLM P54132 2/20 0.36
PMP22 Q01453 2/20 0.36
ALOX15 P16050 1/20 0.36
TAS2R38 P59533 1/20 0.35
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
HSD17B10 Q99714 3/20 0.31
CYP3A4 P08684 2/20 0.31
HPGD P15428 2/20 0.31
NFKB1 P19838 2/20 0.31
EHMT2 Q96KQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL1131239 0.91 ALDH1A1 (0.55) ALDH1A1TSHRLMNATDP1ATM
Urea SCHEMBL28602962 0.91 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1ATM
Urea SCHEMBL653170 0.91
Urea SCHEMBL1308629 0.86
Urea SCHEMBL36685 0.85
Urea SCHEMBL687586 0.85
Thiourea SCHEMBL11869817 0.85
Urea SCHEMBL4454525 0.85 LMNA (0.75) ALDH1A1TSHRLMNATDP1OR51E2
Thiourea SCHEMBL110431 0.85
Thiourea SCHEMBL27335778 0.85 TSHR (0.75) ALDH1A1TSHRATMATRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1106730-B1 Treatment composition which provides anti-wrinkling properties to textiles NAT STARCH CHEM INVEST (US) 2005-11-16 EP disclosed
EP-1106730-A1 Treatment composition which provides anti-wrinkling properties to textiles National Starch and Chemical Investment Holding Corporation (US) 2001-06-13 EP disclosed
EP-0857188-A4 SELF-DISPERSING CURABLE EPOXY RESIN ESTERS HENKEL CORP (US) 1999-02-03 EP disclosed
EP-0857188-A1 SELF-DISPERSING CURABLE EPOXY RESIN ESTERS HENKEL CORPORATION (US) 1998-08-12 EP disclosed
WO-1997015615-A1 SELF-DISPERSING CURABLE EPOXY RESIN ESTERS HENKEL CORPORATION (US) 1997-05-01 WO disclosed