SCHEMBL6264368

SCHEMBL6264368

CCCCC(O)(C(N)=O)c1ccccc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 3/20 0.62
SCN9A Q15858 3/20 0.62
KIF11 P52732 5/20 0.49
KMT2A Q03164 2/20 0.48
MAPT P10636 2/20 0.48
GAA P10253 1/20 0.45
HTT P42858 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
LMNA P02545 2/20 0.42
CHRM2 P08172 2/20 0.42
CHRM1 P11229 2/20 0.42
CHRM3 P20309 2/20 0.42
CYP2D6 P10635 1/20 0.42
KCNH2 Q12809 1/20 0.42
KDM4E B2RXH2 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
CHRM4 P08173 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6258957 0.95 SCN5A (0.69) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL5135543 0.93 SCN5A (0.72) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL13946503 0.93 SCN5A (0.72) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL19205720 0.89 SCN5A (0.54) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL9704438 0.85 GAA (0.51) SCN5ASCN9AKIF11KMT2AGAA
SCHEMBL2517312 0.85 KIF11 (0.48) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL20541470 0.84 HTT (0.54) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL2984162 0.82 CHRM3 (0.56) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL13946506 0.81 MAPT (0.55) SCN5ASCN9AKIF11KMT2AMAPT
SCHEMBL13946510 0.81 MAPT (0.55) SCN5ASCN9AKIF11KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005085182-A1 DL-HYDROXYBENZENAMIDES HAVING ANTICONVULSIVE ACTIVITY MEZA TOLEDO SERGIO ENRIQUE (MX) 2005-09-15 WO disclosed
EP-0476007-A4 CATALYTIC ANTIBODIES 1992-05-20 EP disclosed
EP-0476007-A1 CATALYTIC ANTIBODIES THERAPEUTIC ANTIBODIES INC. (US) 1992-03-25 EP disclosed
WO-1990015134-A1 CATALYTIC ANTIBODIES THERAPEUTIC ANTIBODIES, INC. (US) 1990-12-13 WO disclosed