SCHEMBL3837958

SCHEMBL3837958

CCC(O)(C(N)=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
HTT P42858 2/20 0.46
SCN5A Q14524 3/20 0.45
SCN9A Q15858 3/20 0.45
KCNN4 O15554 3/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
KIF11 P52732 1/20 0.44
GLS O94925 4/20 0.43
CHRM2 P08172 2/20 0.42
CHRM1 P11229 2/20 0.42
CHRM3 P20309 2/20 0.42
LMNA P02545 2/20 0.42
CHRM4 P08173 1/20 0.42
CYP2D6 P10635 1/20 0.42
KCNH2 Q12809 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13946506 1.00 MAPT (0.55) MAPTKMT2AHTTSCN5ASCN9A
SCHEMBL13946510 1.00 MAPT (0.55) MAPTKMT2AHTTSCN5ASCN9A
Benzoic Acid SCHEMBL30973625 0.91 TSHR (0.48) MAPTKMT2AHTTSCN5ASCN9A
Piperazine SCHEMBL10694183 0.89 KMT2A (0.46) MAPTKMT2AHTTSCN5ASCN9A
SCHEMBL19205720 0.84 SCN5A (0.54) MAPTKMT2AHTTSCN5ASCN9A
SCHEMBL584028 0.83 CYP2C19 (0.47) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL7899580 0.83 CYP2C19 (0.47) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL5570579 0.83 CYP2C19 (0.47) MAPTKMT2AHTTKCNN4CYP2C19
SCHEMBL8360666 0.82 SCN5A (0.49) MAPTKMT2ASCN5ASCN9AHIF1A
SCHEMBL5898532 0.82 CES2 (0.44) KMT2ASCN5ASCN9ACYP2C19KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4525820-A1 ANTICAKING COMPOSITION AND METHOD FOR IMPROVING FLOWING PROPERTIES OF HYGROSCOPIC TIN SALTS HONEYWELL INTERNATIONAL INC. (US) 2025-03-26 EP disclosed
CN-114245016-B Control method and system for video shooting, computer equipment and storage medium 睿魔智能科技(深圳)有限公司 2024-10-18 CN disclosed
WO-2024015247-A1 ANTICAKING COMPOSITION AND METHOD FOR IMPROVING FLOWING PROPERTIES OF HYGROSCOPIC TIN SALTS HONEYWELL INTERNATIONAL INC. (US) 2024-01-18 WO disclosed
US-20240009094-A1 ANTICAKING COMPOSITION AND METHOD FOR IMPROVING FLOWING PROPERTIES OF HYGROSCOPIC TIN SALTS HONEYWELL INTERNATIONAL INC. (US) 2024-01-11 US disclosed
CN-117003665-A Synthesis process of N, N-diethyl-2-hydroxy-2-phenylacetamide 百新(北京)药业科技有限责任公司 2023-11-07 CN disclosed
CN-110791509-B Pediococcus acidilactici optimized expression sequence, expression vector, preparation method and strain thereof 深圳市圣西马生物技术有限公司 2023-09-08 CN disclosed
US-8350076-B2 Sodium channel blockers UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2013-01-08 US disclosed
EP-2097385-A1 2-[1-PHENYL-5-HYDROXY OR METHOXY-4ALPHA-METHYL-HEXAHYDROCLOPENTA[F]INDAZOL-5-YL]ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS Merck & Co., Inc. (US) 2009-09-09 EP disclosed
CN-101511840-A Phosphoinositide 3-kinase inhibitor compounds and methods of use thereof GENENTECH INC (US) 2009-08-19 CN disclosed
US-20090030056-A1 NOVEL SODIUM CHANNEL BLOCKERS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2009-01-29 US disclosed
US-7439383-B2 Sodium channel blockers UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-10-21 US disclosed
US-7414078-B2 Oral general anesthetics and metabolitically resistant anticonvulsants UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2008-08-19 US disclosed
WO-2008051532-A1 2-[1-PHENYL-5-HYDROXY OR METHOXY-4ALPHA-METHYL-HEXAHYDROCLOPENTA[F]INDAZOL-5-YL]ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS MERCK & CO., INC. (US) 2008-05-02 WO disclosed
US-20060287397-A1 Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity MEZA TOLEDO SERGIO E 2006-12-21 US disclosed
WO-1997023202-A1 SUBTYPE-SELECTIVE NMDA RECEPTOR LIGANDS AND THE USE THEREOF STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITYA ND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1997-07-03 WO disclosed
US-5463125-A 3-hydroxy-3-phenylpentamide SANDOVAL GUILLERMO C (MX) 1995-10-31 US disclosed
US-5463125-A 3-hydroxy-3-phenylpentamide SANDOVAL GUILLERMO C (MX) 1995-10-31 US disclosed
US-4889853-A CEREBRAL INSUFFICIENCY; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS; ANTIHYPOXIA AGENTS SUNTORY LIMITED (JP) 1989-12-26 US disclosed
EP-0298758-A2 Hydroquinonylphenyl butyric acid amide derivative SUNTORY LIMITED (JP) 1989-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287397-A1 Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity GABRB2, HRH3, HRH4 MAPT 2331/4885KMT2A 211/4885HTT 595/4885
US-20090030056-A1 NOVEL SODIUM CHANNEL BLOCKERS SCNN1B, SCN1B, KCNN2 MAPT 2919/4885KMT2A 3061/4885HTT 3895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.