Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.77 |
| ▸ | MMP9 | P14780 | 4/20 | 0.77 |
| ▸ | MMP8 | P22894 | 4/20 | 0.77 |
| ▸ | MMP13 | P45452 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 5/20 | 0.61 |
| ▸ | GFER | P55789 | 4/20 | 0.61 |
| ▸ | GLA | P06280 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260769 | 0.87 | MMP2 (1.00) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL9862039 | 0.86 | ALDH1A1 (0.69) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL28312335 | 0.86 | ALDH1A1 (0.74) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL159873 | 0.86 | ALDH1A1 (0.74) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL30307784 | 0.86 | ALDH1A1 (0.74) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL1655753 | 0.84 | MEN1 (0.73) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL30533210 | 0.84 | MEN1 (0.73) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL7652407 | 0.84 | MMP13 (0.56) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL3337505 | 0.84 | ALDH1A1 (0.55) | MMP2MMP9MMP8MMP13SMN1; SMN2 | |
| SCHEMBL27236921 | 0.84 | MMP2 (0.55) | MMP2MMP9MMP8MMP13MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042496-A1 | (BENZIMIDAZOL-2-YL)-PHENYL-BENZYL-AMINE DERIVATIVES AND METHODS FOR INHIBITING HEPARANASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-05-12 | — | — | WO | disclosed |
| WO-2005030206-A1 | ARYL-1,3-AZOLE DERIVATIVES AND METHODS FOR INHIBITING HEPARNASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |