SCHEMBL6264576

SCHEMBL6264576

C[Si](Cc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.42
NR1H3 Q13133 2/20 0.42
TP53 P04637 1/20 0.42
CALM1 P0DP23 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
TSHR P16473 4/20 0.37
ALDH1A1 P00352 3/20 0.37
IDO1 P14902 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
TRPA1 O75762 1/20 0.36
KDM4E B2RXH2 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14480308 0.89 NR1H2 (0.39) NR1H2NR1H3TP53CALM1ESR1
SCHEMBL18711459 0.87 NR1H2 (0.38) NR1H2NR1H3TP53ESR1ESR2
SCHEMBL9137855 0.82 LTA4H (0.47) TDP1CYP3A4
SCHEMBL3839629 0.80 NR1H2 (0.59) NR1H2NR1H3TP53CALM1ESR1
Hydrochloric Acid SCHEMBL8045525 0.78 NR1H2 (0.58) NR1H2NR1H3TP53CALM1ESR1
SCHEMBL4682428 0.76 NR1H2 (0.40) NR1H2NR1H3TP53CALM1ESR1
SCHEMBL1270651 0.76 ESR1 (0.42) NR1H2NR1H3TP53CALM1ESR1
SCHEMBL16378246 0.76 TP53 (0.48) NR1H2NR1H3TP53CALM1TSHR
SCHEMBL1107767 0.76 TP53 (0.48) NR1H2NR1H3TP53CALM1TSHR
SCHEMBL9225762 0.76 ESR1 (0.42) NR1H2NR1H3TP53CALM1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038143-B2 Polymer compound, material for electronic elements, material for organic electroluminescent elements, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-07-31 US disclosed
US-20150249215-A1 POLYMER COMPOUND, MATERIAL FOR ELECTRONIC ELEMENTS, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 US disclosed
EP-1431314-B1 process for the living radical polymerization of olefinically unsaturated monomers ENI SPA (IT) 2005-11-16 EP disclosed
EP-1431314-A2 Process for the living radical polymerization of oliffinically unsaturated monomers ENI S.p.A. (IT) 2004-06-23 EP disclosed