Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GNPAT | O15228 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.49 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.49 |
| ▸ | GRN | P28799 | 1/20 | 0.49 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | LAP3 | P28838 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572561 | 1.00 | FOLH1 (0.64) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4572547 | 0.89 | FOLH1 (0.60) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL15680095 | 0.89 | FOLH1 (0.60) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL15623775 | 0.86 | ALDH1A1 (0.62) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL26353950 | 0.85 | FOLH1 (0.47) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6256944 | 0.85 | ALDH1A1 (0.60) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL4027352 | 0.85 | PLA2G2A (0.61) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL5159794 | 0.85 | ALDH1A1 (0.60) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6256947 | 0.85 | ALDH1A1 (0.60) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL25507281 | 0.85 | ALDH1A1 (0.60) | FOLH1ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211883-A1 | SYRBACTIN MACROLACTAMS AND UNNATURAL ANALOGS AS PROTEASOME INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA AND CHEMOENZYMATIC SYNTHESIS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-11-02 | — | — | WO | disclosed |
| EP-1599103-A1 | AMINOACID DERIVATIVES OF DICARBOXYLIC ACIDS AS FLAVOR INGREDIENTS | FIRMENICH SA (CH) | 2005-11-30 | — | — | EP | disclosed |
| US-20050233058-A1 | Aminoacid derivatives of dicarboxylic acids as flavor ingredients | FIRMENICH SA (CH) | 2005-10-20 | — | — | US | disclosed |
| WO-2004075663-A1 | AMINOACID DERIVATIVES OF DICARBOXYLIC ACIDS AS FLAVOR INGREDIENTS | FIRMENICH SA (CH) | 2004-09-10 | — | — | WO | disclosed |