Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 10/20 | 0.59 |
| ▸ | CA12 | O43570 | 7/20 | 0.59 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NDUFS8 | O00217 | 2/20 | 0.48 |
| ▸ | COXFA4 | O00483 | 2/20 | 0.48 |
| ▸ | NDUFAB1 | O14561 | 2/20 | 0.48 |
| ▸ | NDUFA1 | O15239 | 2/20 | 0.48 |
| ▸ | NDUFS4 | O43181 | 2/20 | 0.48 |
| ▸ | NDUFB5 | O43674 | 2/20 | 0.48 |
| ▸ | NDUFB3 | O43676 | 2/20 | 0.48 |
| ▸ | NDUFC1 | O43677 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262163 | 1.00 | CA9 (0.59) | CA9CA12CA1CA7MCL1 | |
| SCHEMBL6268109 | 1.00 | CA9 (0.59) | CA9CA12CA1CA7MCL1 | |
| SCHEMBL6268111 | 1.00 | CA9 (0.59) | CA9CA12CA1CA7MCL1 | |
| SCHEMBL6267768 | 0.91 | NDUFS8 (0.55) | CA9CA12ALOX15NDUFS8COXFA4 | |
| SCHEMBL8526039 | 0.90 | KDM4E (0.53) | CA9CA12CA1CA7CA2 | |
| SCHEMBL1095981 | 0.86 | CA12 (0.63) | CA9CA12CA1CA7CA2 | |
| SCHEMBL4293165 | 0.86 | CA12 (0.63) | CA9CA12CA1CA7CA2 | |
| SCHEMBL19831442 | 0.86 | CA12 (0.63) | CA9CA12CA1CA7CA2 | |
| SCHEMBL21043916 | 0.84 | CA12 (0.64) | CA9CA12CA1CA7CA2 | |
| SCHEMBL6018753 | 0.83 | CA12 (0.68) | CA9CA12CA1CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455268-A | Treating arthropathy | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-10-03 | — | — | US | claimed |
| WO-2005091960-A2 | METHOD FOR INHIBITING FIBROCARTILAGE DEGRADATION | RUSH UNIVERSITY MEDICAL CENTER (US) | 2005-10-06 | — | — | WO | disclosed |
| EP-0614896-B1 | Esculetin derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5455268-A | Treating arthropathy | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-10-03 | — | — | US | disclosed |
| EP-0614896-A1 | Esculetin derivatives and pharmaceutical composition | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |