Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NDUFS8 | O00217 | 3/20 | 0.55 |
| ▸ | COXFA4 | O00483 | 3/20 | 0.55 |
| ▸ | NDUFAB1 | O14561 | 3/20 | 0.55 |
| ▸ | NDUFA1 | O15239 | 3/20 | 0.55 |
| ▸ | NDUFS4 | O43181 | 3/20 | 0.55 |
| ▸ | NDUFB5 | O43674 | 3/20 | 0.55 |
| ▸ | NDUFB3 | O43676 | 3/20 | 0.55 |
| ▸ | NDUFC1 | O43677 | 3/20 | 0.55 |
| ▸ | NDUFA2 | O43678 | 3/20 | 0.55 |
| ▸ | NDUFS5 | O43920 | 3/20 | 0.55 |
| ▸ | NDUFS7 | O75251 | 3/20 | 0.55 |
| ▸ | NDUFS2 | O75306 | 3/20 | 0.55 |
| ▸ | NDUFS6 | O75380 | 3/20 | 0.55 |
| ▸ | NDUFB1 | O75438 | 3/20 | 0.55 |
| ▸ | NDUFS3 | O75489 | 3/20 | 0.55 |
| ▸ | NDUFB6 | O95139 | 3/20 | 0.55 |
| ▸ | NDUFA3 | O95167 | 3/20 | 0.55 |
| ▸ | NDUFB4 | O95168 | 3/20 | 0.55 |
| ▸ | NDUFB8 | O95169 | 3/20 | 0.55 |
| ▸ | NDUFB2 | O95178 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268111 | 0.91 | CA9 (0.59) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL6268109 | 0.91 | CA9 (0.59) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL6264815 | 0.91 | CA9 (0.59) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL6262163 | 0.91 | CA9 (0.59) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL28061786 | 0.86 | NDUFS8 (0.58) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL12081709 | 0.85 | NDUFS8 (0.57) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL28529405 | 0.85 | NDUFS8 (0.57) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL712741 | 0.85 | NDUFS8 (0.57) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL8527989 | 0.83 | ALDH1A1 (0.52) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL18422152 | 0.82 | ELANE (0.46) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455268-A | Treating arthropathy | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-10-03 | — | — | US | claimed |
| WO-2005091960-A2 | METHOD FOR INHIBITING FIBROCARTILAGE DEGRADATION | RUSH UNIVERSITY MEDICAL CENTER (US) | 2005-10-06 | — | — | WO | disclosed |
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |
| EP-0614896-B1 | Esculetin derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5455268-A | Treating arthropathy | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-10-03 | — | — | US | disclosed |
| EP-0614896-A1 | Esculetin derivatives and pharmaceutical composition | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-09-14 | — | — | EP | disclosed |