Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | GLA | P06280 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265537 | 0.92 | KDM4E (0.61) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6265896 | 0.92 | KDM4E (0.61) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6264833 | 0.92 | KDM4E (0.61) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6267523 | 0.92 | KDM4E (0.61) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6262163 | 0.90 | CA9 (0.59) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6264815 | 0.90 | CA9 (0.59) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6268109 | 0.90 | CA9 (0.59) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6268111 | 0.90 | CA9 (0.59) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL8527989 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6267768 | 0.82 | NDUFS8 (0.55) | KDM4EALDH1A1HPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614896-B1 | Esculetin derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 1998-12-30 | — | — | EP | disclosed |