Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 13/20 | 0.51 |
| ▸ | NAMPT | P43490 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264932 | 1.00 | DRD2 (0.51) | DRD2DRD3CCR2NAMPTCYP3A4 | |
| SCHEMBL3067463 | 0.85 | DRD3 (0.65) | DRD2DRD3 | |
| SCHEMBL88279 | 0.85 | DRD3 (0.65) | DRD2DRD3 | |
| SCHEMBL6266237 | 0.84 | DRD3 (0.54) | DRD2DRD3CCR2NAMPTCYP3A4 | |
| SCHEMBL6266232 | 0.84 | DRD3 (0.54) | DRD2DRD3CCR2NAMPTCYP3A4 | |
| SCHEMBL6270127 | 0.84 | CCR2 (0.59) | DRD2DRD3CCR2NAMPTCYP3A4 | |
| SCHEMBL6264255 | 0.82 | DRD3 (0.55) | DRD2DRD3CCR2NAMPTCYP3A4 | |
| SCHEMBL6264257 | 0.82 | DRD3 (0.55) | DRD2DRD3CCR2NAMPTCYP3A4 | |
| SCHEMBL87847 | 0.82 | DRD3 (0.57) | DRD2DRD3CCR2NAMPTCYP3A4 | |
| SCHEMBL3079587 | 0.82 | DRD3 (0.57) | DRD2DRD3CCR2NAMPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079832-B1 | USE OF VITAMIN PP COMPOUNDS | KLINGE CO CHEM PHARM FAB (DE) | 2005-11-30 | — | — | EP | claimed |