Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88313 | 0.86 | CCR2 (0.81) | CCR2DRD2DRD3 | |
| SCHEMBL88314 | 0.86 | CCR2 (0.81) | CCR2DRD2DRD3 | |
| SCHEMBL83120 | 0.86 | DRD3 (0.62) | CCR2DRD2DRD3CYP3A4CYP2C9 | |
| SCHEMBL3079779 | 0.86 | DRD3 (0.62) | CCR2DRD2DRD3CYP3A4CYP2C9 | |
| SCHEMBL3090708 | 0.84 | DRD2 (0.71) | DRD2DRD3 | |
| SCHEMBL82403 | 0.84 | DRD2 (0.71) | DRD2DRD3 | |
| SCHEMBL6264932 | 0.84 | DRD2 (0.51) | CCR2DRD2DRD3CYP3A4CYP2C9 | |
| SCHEMBL6264935 | 0.84 | DRD2 (0.51) | CCR2DRD2DRD3CYP3A4CYP2C9 | |
| SCHEMBL6267972 | 0.82 | DRD3 (0.57) | CCR2DRD2DRD3CYP3A4CYP2C9 | |
| SCHEMBL6267971 | 0.82 | DRD3 (0.57) | CCR2DRD2DRD3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079832-B1 | USE OF VITAMIN PP COMPOUNDS | KLINGE CO CHEM PHARM FAB (DE) | 2005-11-30 | — | — | EP | claimed |