Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274922 | 0.79 | ACHE (0.46) | ACHEALDH1A1TDP1IDO1EP300 | |
| SCHEMBL5277342 | 0.79 | ACHE (0.38) | ACHEALDH1A1TDP1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL5406241 | 0.79 | ACHE (0.38) | ACHEALDH1A1TDP1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL5403999 | 0.79 | ACHE (0.38) | ACHEALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL5272686 | 0.74 | ACHE (1.00) | ACHETDP1CYP3A4HSD17B10 | |
| SCHEMBL5277348 | 0.73 | IDO1 (0.45) | ACHEALDH1A1IDO1 | |
| SCHEMBL29399235 | 0.73 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL48945 | 0.73 | ALDH1A1 (1.00) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL31667846 | 0.73 | ALDH1A1 (0.68) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL5406243 | 0.72 | IDO1 (0.44) | ACHEALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587793-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004069804-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2004-08-19 | — | — | WO | disclosed |