Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4890647 | 0.88 | KDM4E (0.51) | FAAHDGKACNR2KDM4EDUSP3 | |
| SCHEMBL4893171 | 0.88 | KDM4E (0.51) | FAAHDGKACNR2KDM4EDUSP3 | |
| SCHEMBL4893811 | 0.88 | KDM4E (0.51) | FAAHDGKACNR2KDM4EDUSP3 | |
| SCHEMBL4892938 | 0.85 | KDM4E (0.47) | FAAHDGKACNR2KDM4EDUSP3 | |
| SCHEMBL7574622 | 0.81 | DGKA (0.65) | FAAHDGKASELPKDM4EDUSP3 | |
| Glyceryl Monolinoleate SCHEMBL19564919 | 0.75 | FAAH (0.92) | FAAHDGKASELPKDM4EDUSP3 | |
| Glyceryl Monolinoleate SCHEMBL154133 | 0.75 | FAAH (0.92) | FAAHDGKASELPKDM4EDUSP3 | |
| Glyceryl Monolinoleate SCHEMBL4350267 | 0.75 | FAAH (0.92) | FAAHDGKASELPKDM4EDUSP3 | |
| Glyceryl Monolinoleate SCHEMBL6371582 | 0.75 | FAAH (0.92) | FAAHDGKASELPKDM4EDUSP3 | |
| SCHEMBL10011646 | 0.75 | FAAH (0.52) | FAAHDGKAALDH1A1KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | disclosed |