Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149576 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL4566397 | 0.70 | — | — | |
| SCHEMBL4473097 | 0.69 | HDAC2 (0.34) | — | |
| SCHEMBL5105795 | 0.68 | ALOX15 (0.33) | — | |
| SCHEMBL6205350 | 0.67 | GSR (0.39) | POLB | |
| SCHEMBL4470930 | 0.65 | ALOX15 (0.32) | — | |
| SCHEMBL3997979 | 0.64 | TSHR (0.39) | HTT | |
| SCHEMBL4478476 | 0.64 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL8588110 | 0.63 | — | — | |
| SCHEMBL4489884 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567528-A1 | MIXED LINEAGE KINASE MODULATORS | ELI LILLY AND COMPANY (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048383-A1 | MIXED LINEAGE KINASE MODULATORS | ELI LILLY AND COMPANY (US) | 2004-06-10 | — | — | WO | disclosed |