Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105795 | 0.85 | ALOX15 (0.33) | ALOX15 | |
| SCHEMBL149576 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL4489884 | 0.79 | — | — | |
| SCHEMBL2038948 | 0.79 | ALOX15 (0.42) | ALOX15 | |
| SCHEMBL4489489 | 0.79 | NLRP3 (0.31) | ALOX15 | |
| SCHEMBL6320611 | 0.78 | ALDH1A1 (0.44) | ALOX15 | |
| SCHEMBL4473097 | 0.75 | HDAC2 (0.34) | — | |
| SCHEMBL4487670 | 0.75 | HTR1A (0.36) | — | |
| SCHEMBL523503 | 0.74 | HRH3 (0.36) | — | |
| SCHEMBL11331244 | 0.73 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803474-A | Beta-cell replication promoting compounds and methods of their use | HARVARD COLLEGE | 2012-11-28 | — | — | CN | disclosed |
| US-7511065-B2 | Mixed lineage kinase modulators | ELI LILLY AND COMPANY (US) | 2009-03-31 | — | — | US | disclosed |
| US-20080113977-A1 | Mixed Lineage Kinase Modulators | ELI LILLY AND COMPANY | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113977-A1 | Mixed Lineage Kinase Modulators | MYLK2, CSNK1G2, CSNK1A1 | ALOX15 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.