Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 10/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15119810 | 0.89 | RAB9A (0.57) | CNR2TAS1R3TAS1R1RAB9A | |
| SCHEMBL13896418 | 0.82 | RAB9A (0.59) | CNR2RAB9A | |
| SCHEMBL5315168 | 0.77 | TAS1R3 (0.65) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL5793451 | 0.77 | TAS1R3 (0.65) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL15444816 | 0.77 | TAS1R3 (0.56) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL15444811 | 0.73 | TAS1R3 (0.52) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL10226929 | 0.71 | TAS1R3 (1.00) | CNR2TAS1R3TAS1R1CNR1RAB9A | |
| SCHEMBL26414747 | 0.71 | RAB9A (0.76) | RAB9A | |
| SCHEMBL20774154 | 0.70 | CRBN (0.62) | CNR2 | |
| SCHEMBL20779009 | 0.70 | CRBN (0.62) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567150-A1 | DERIVATIVES OF INDOLE-3-CARBOXAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050086-A1 | DERIVATIVES OF INDOLE-3-CARBOXAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-06-17 | — | — | WO | disclosed |