Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265371 | 0.81 | TDP1 (0.50) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL28032287 | 0.73 | CES1 (0.44) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL11177590 | 0.72 | PPARG (0.50) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL3205527 | 0.71 | TDP1 (0.48) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL9578308 | 0.69 | TDP1 (0.56) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL10781749 | 0.69 | TDP1 (0.56) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL2098567 | 0.69 | TDP1 (0.56) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL10781459 | 0.69 | TDP1 (0.56) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL599761 | 0.68 | TDP1 (0.61) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL1704713 | 0.68 | TDP1 (0.61) | TDP1L3MBTL1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224467-B1 | PROTECTING ALKYLATING REAGENTS USED FOR QUANTIFYING HOMOCYSTEINE | DADE BEHRING MARBURG GMBH (DE) | 2005-11-30 | — | — | EP | disclosed |
| US-20040198703-A1 | Protecting groups for biological labeling | KECZER STEYE DE (US) | 2004-10-07 | — | — | US | disclosed |
| US-6783947-B1 | FOR DETECTING AMOUNT OF HOMOCYSTEINE IN SAMPLE; COMPRISES ALPHA-HALOKETONE AND DEPROTECTING AGENTS; FOR BIOASSAYS/CONJUGATION KITS | DADE BEHRING MARBURG GMBH (DE) | 2004-08-31 | — | — | US | disclosed |
| EP-1224467-A2 | PROTECTING ALKYLATING REAGENTS USED FOR QUANTIFYING HOMOCYSTEINE | Dade Behring Marburg GmbH (DE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001018548-A2 | PROTECTING ALKYLATING REAGENTS USED FOR QUANTIFYING HOMOCYSTEINE | DADE BEHRING MARBURG GMBH (DE) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198703-A1 | Protecting groups for biological labeling | MGMT, PTMS, BCKDK | TDP1 1684/4885L3MBTL1 1035/4885CES2 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.