SCHEMBL3205527

SCHEMBL3205527

O=C(c1ccccc1)C(Sc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CES2 O00748 3/20 0.47
CES1 P23141 3/20 0.47
LMNA P02545 3/20 0.47
ALKBH5 Q6P6C2 1/20 0.44
MDM2 Q00987 1/20 0.44
ALDH1A1 P00352 5/20 0.42
TSHR P16473 2/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
HPGD P15428 3/20 0.41
MAPT P10636 2/20 0.41
PLIN1 O60240 1/20 0.41
HTT P42858 1/20 0.41
PLIN5 Q00G26 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ABHD5 Q8WTS1 1/20 0.41
POLB P06746 2/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965136 0.79 LMNA (0.46) L3MBTL1LMNAALDH1A1HPGDMAPT
SCHEMBL1357707 0.79 TDP1 (0.45) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL10779384 0.79 ADORA2A (0.53) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL10882291 0.78 LMNA (0.59) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL2025571 0.76 PGR (0.43) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL28497982 0.76 TSHR (0.44) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL6265371 0.76 TDP1 (0.50) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL6686346 0.76 EPHX1 (0.45) TDP1L3MBTL1LMNATSHRMAPT
SCHEMBL28763735 0.72 MAPT (0.41) TDP1L3MBTL1CES2CES1LMNA
SCHEMBL11610405 0.72 SLC6A2 (0.48) TDP1L3MBTL1CES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180011401-A1 SULFONIC ACID DERIVATIVE, PHOTOACID GENERATOR USING SAME, RESIST COMPOSITION, AND DEVICE MANUFACTURING METHOD TOYO GOSEI CO., LTD. (JP) 2018-01-11 US disclosed
US-9714217-B2 Sulfonic acid derivative and photoacid generator TOYO GOSEI CO., LTD. (JP) 2017-07-25 US disclosed
US-20130130175-A1 Compound for Photoacid Generator, Resist Composition Using the Same, and Pattern-Forming Method CENTRAL GLASS COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-8435717-B2 Compound for photoacid generator, resist composition using the same, and pattern-forming method CENTRAL GLASS COMPANY, LIMITED (JP) 2013-05-07 US disclosed
US-20120289738-A1 SULFONIC ACID DERIVATIVE AND PHOTOACID GENERATOR TOYO GOSEI CO., LTD. (JP) 2012-11-15 US disclosed
US-20100035185-A1 Compound for Photoacid Generator, Resist Composition Using the Same, and Pattern-Forming Method CENTRAL GLASS COMPANY, LTD. (JP) 2010-02-11 US disclosed
US-7414148-B2 Process for producing alkoxycarbonylfluoroalkanesulfonates CENTRAL GLASS COMPANY LIMITED (JP) 2008-08-19 US disclosed
US-20080108846-A1 PROCESS FOR PRODUCING ALKOXYCARBONYLFLUOROALKANESULFONATES CENTRAL GLASS COMPANY, LIMITED (JP) 2008-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180011401-A1 SULFONIC ACID DERIVATIVE, PHOTOACID GENERATOR USING SAME, RESIST COMPOSITION, AND DEVICE MANUFACTURING METHOD ASIC1, ASIC3, CRY1 TDP1 4756/4885L3MBTL1 4346/4885CES2 991/4885
US-20080108846-A1 PROCESS FOR PRODUCING ALKOXYCARBONYLFLUOROALKANESULFONATES ARSA, PFAS, MPST TDP1 4653/4885L3MBTL1 4866/4885CES2 664/4885
US-20100035185-A1 Compound for Photoacid Generator, Resist Composition Using the Same, and Pattern-Forming Method ASIC1, RER1, INSRR TDP1 2802/4885L3MBTL1 4479/4885CES2 3810/4885
US-20120289738-A1 SULFONIC ACID DERIVATIVE AND PHOTOACID GENERATOR CRY1, ASIC1, ASIC3 TDP1 4851/4885L3MBTL1 3903/4885CES2 2643/4885
US-20130130175-A1 Compound for Photoacid Generator, Resist Composition Using the Same, and Pattern-Forming Method ASIC1, RER1, INSRR TDP1 2704/4885L3MBTL1 4435/4885CES2 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.