Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265665 | 0.74 | RAB9A (0.54) | LMNATP53RAB9AHTTPIP4K2A | |
| SCHEMBL6265666 | 0.73 | PIP4K2A (0.57) | LMNATP53RAB9AHTTPIP4K2A | |
| SCHEMBL6263777 | 0.72 | RAB9A (0.70) | LMNATP53RAB9AHTTPIP4K2A | |
| SCHEMBL6271125 | 0.69 | MAPT (0.82) | LMNATP53RAB9APIP4K2AKDM4E | |
| SCHEMBL30723333 | 0.67 | FSCN1 (1.00) | LMNATP53HTTKDM4EFSCN1 | |
| SCHEMBL15521859 | 0.67 | FSCN1 (1.00) | LMNATP53HTTKDM4EFSCN1 | |
| SCHEMBL6264348 | 0.67 | PIP4K2A (0.76) | LMNATP53PIP4K2AKDM4EMAPT | |
| SCHEMBL839601 | 0.67 | RAB9A (0.55) | LMNATP53RAB9AHTTPIP4K2A | |
| SCHEMBL29306049 | 0.67 | RAB9A (0.98) | LMNATP53RAB9AHTTPIP4K2A | |
| SCHEMBL6265421 | 0.67 | MAPT (1.00) | LMNATP53HTTPIP4K2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |