Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264348 | 0.74 | PIP4K2A (0.76) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6265668 | 0.73 | LMNA (0.59) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6265665 | 0.73 | RAB9A (0.54) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6279977 | 0.72 | PIP4K2A (0.72) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6271125 | 0.72 | MAPT (0.82) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6263777 | 0.71 | RAB9A (0.70) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6268057 | 0.70 | TP53 (0.71) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL26781491 | 0.70 | HPGD (1.00) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6265421 | 0.69 | MAPT (1.00) | PIP4K2ALMNAMAPTTP53HPGD | |
| SCHEMBL6268047 | 0.69 | KDM4E (0.69) | PIP4K2ALMNAMAPTTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |