SCHEMBL6265673

SCHEMBL6265673

Cc1ccc(CN(C)C)c(O)c1.[LiH]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.59
KDM4E B2RXH2 2/20 0.59
ALDH1A1 P00352 2/20 0.59
MEN1 O00255 1/20 0.59
POLB P06746 1/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 1/20 0.59
THRB P10828 1/20 0.59
G6PD P11413 1/20 0.59
PABPC1 P11940 1/20 0.59
KMT2A Q03164 1/20 0.59
HKDC1 Q2TB90 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TRPA1 O75762 1/20 0.46
SLC6A4 P31645 8/20 0.44
SLC6A2 P23975 4/20 0.44
SLC6A3 Q01959 4/20 0.44
HSD17B10 Q99714 2/20 0.44
ALOX15 P16050 2/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267919 0.98 TDP1 (0.61) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL6265084 0.86 TDP1 (0.61) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL4004859 0.83 TDP1 (0.64) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL6128132 0.78 KDM4E (0.61) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL12074780 0.78 SLC6A4 (0.49) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL11316837 0.77 PYCR1 (0.59) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL4467416 0.76 ALDH1A1 (0.90) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL51100 0.76 AMY1A (0.57) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL8392110 0.76 MEN1 (0.59) TDP1KDM4EALDH1A1MEN1POLB
SCHEMBL29938514 0.76 ALDH1A1 (0.59) TDP1KDM4EALDH1A1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005087901-A2 FUEL ADDITIVE COMPOSITION HAVING ANTIKNOCK PROPERTIES INNOSPEC LIMITED (GB) 2005-09-22 WO disclosed