Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADK | P55263 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ATG7 | O95352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267131 | 1.00 | HIF1A (0.49) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL5982945 | 0.86 | SLC29A1 (0.50) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL5982938 | 0.86 | SLC29A1 (0.50) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL5982268 | 0.81 | HIF1A (0.71) | HIF1ATP53SMN1; SMN2PDE4DPNP | |
| SCHEMBL5982275 | 0.81 | HIF1A (0.71) | HIF1ATP53SMN1; SMN2PDE4DPNP | |
| SCHEMBL8804083 | 0.78 | ADORA3 (0.58) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL8804074 | 0.78 | ADORA3 (0.58) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL5983171 | 0.78 | HIF1A (0.44) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL5983176 | 0.78 | HIF1A (0.44) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 | |
| SCHEMBL5983420 | 0.77 | KDM4E (0.48) | HIF1AADORA3ADORA2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1600452-A2 | Synthesis of 2'-deoxy-L-nucleosides | Pharmasset Limited (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1600451-A2 | Synthesis of 2'-deoxy-l-nucleosides | Pharmasset Limited (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20050090660-A1 | 2'-deoxy-L-nucleosides | PHARMASSET, INC. | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090660-A1 | 2'-deoxy-L-nucleosides | CCNH, ADAR, NSUN2 | HIF1A 2249/4885ADORA3 14/4885ADORA2A 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.