Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265246 | 0.81 | ADAMTS5 (0.42) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL6276393 | 0.81 | ADAMTS5 (0.44) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL12010977 | 0.75 | ADAMTS5 (0.49) | MAPTALDH1A1KDM4ENPSR1NPC1 | |
| SCHEMBL6275809 | 0.70 | RAF1 (0.37) | KMT2AMAPTALDH1A1MEN1HPGD | |
| SCHEMBL6272309 | 0.69 | ADAMTS5 (0.38) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL6272380 | 0.69 | ADAMTS5 (0.46) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL171741 | 0.69 | L3MBTL1 (0.83) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| Biphenyl SCHEMBL9009636 | 0.67 | NAPRT (0.86) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL6266093 | 0.66 | ADAMTS5 (0.40) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| Acetanilide SCHEMBL24681 | 0.65 | NAPRT (1.00) | KMT2AMAPTALDH1A1MEN1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |