Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 7/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267381 | 0.89 | ADAMTS5 (0.41) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6278069 | 0.88 | NPC1 (0.38) | ADAMTS5ALDH1A1NPY5RRAB9ACYP19A1 | |
| SCHEMBL6265204 | 0.79 | ADAMTS5 (0.37) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6262704 | 0.78 | ADAMTS5 (0.49) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6277990 | 0.77 | ADAMTS5 (0.47) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6260436 | 0.77 | MECP2 (0.47) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6274347 | 0.75 | ADAMTS5 (0.47) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6276922 | 0.72 | KMT2A (0.51) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6387706 | 0.71 | ADAMTS5 (0.40) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6277257 | 0.70 | ADAMTS5 (0.58) | ADAMTS5MAPTL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |