Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270554 | 0.95 | MEN1 (0.40) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL6264555 | 0.89 | MEN1 (0.42) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL6267243 | 0.78 | KMT2A (0.43) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL6271786 | 0.76 | NPC1 (0.45) | MEN1KMT2AALDH1A1MAPK1NPC1 | |
| SCHEMBL6270555 | 0.75 | KMT2A (0.40) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL6271501 | 0.74 | POLB (0.44) | MEN1KMT2AALDH1A1MAPK1NPC1 | |
| SCHEMBL6264556 | 0.73 | CASP3 (0.41) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL3981602 | 0.73 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1MAPK1NPC1 | |
| SCHEMBL6270527 | 0.71 | CASP3 (0.39) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL6264474 | 0.70 | RAB9A (0.48) | KMT2AALDH1A1NPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |