Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MITF | O75030 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031602 | 0.86 | NPC1 (0.68) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL6275004 | 0.85 | DYRK1A (0.58) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL18984451 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL381600 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL1261509 | 0.81 | NPC1 (0.75) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL211024 | 0.79 | RAB9A (0.66) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL19899933 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL9797268 | 0.79 | KDM4E (0.88) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL22924402 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4ENFKB1NFKB2RELA | |
| SCHEMBL1036069 | 0.79 | KDM4E (0.62) | SMN1; SMN2KDM4ENFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100378-A1 | PROCESS FOR THE PREPARATION OF A PEPTIDE, AND COMPOUNDS COMPRISING A THIOESTER CARBOXYL-ACTIVATING GROUP FOR USE THEREIN | AVECIA LIMITED (GB) | 2005-10-27 | — | — | WO | disclosed |
| US-4886738-A | COLOR REVERSAL MATERIAL WITH IMPROVED PUSH DEVELOPABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| US-4322214-A | USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING | ASAHI CHEMICAL COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |