SCHEMBL211024

SCHEMBL211024

Nc1nc2ccc(C(=O)O)cc2s1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.66
NPC1 O15118 3/20 0.66
ALDH1A1 P00352 3/20 0.66
KDM4E B2RXH2 3/20 0.66
MAPT P10636 3/20 0.66
NFKB1 P19838 2/20 0.66
NFKB2 Q00653 2/20 0.66
RELA Q04206 2/20 0.66
GAA P10253 2/20 0.66
GFER P55789 2/20 0.66
HPGD P15428 2/20 0.66
MITF O75030 1/20 0.66
POLB P06746 1/20 0.66
RECQL P46063 1/20 0.66
PAX8 Q06710 1/20 0.66
KLF5 Q13887 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
LMNA P02545 4/20 0.65
SMN1; SMN2 Q16637 2/20 0.62
CYP2D6 P10635 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4680538 0.98 RAB9A (0.64) RAB9ANPC1ALDH1A1KDM4EMAPT
Bromide SCHEMBL10947640 0.98 RAB9A (0.64) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL6985206 0.86 NPC1 (0.68) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL30563626 0.86 RAB9A (0.61) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL3113684 0.86 RAB9A (0.61) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL27549467 0.85 RAB9A (0.59) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL1638828 0.85 RAB9A (0.59) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL7759315 0.84 LMNA (0.67) RAB9ANPC1ALDH1A1KDM4EMAPT
Hydrochloric Acid SCHEMBL10757074 0.83 RAB9A (0.58) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL8243666 0.83 HTT (0.59) RAB9ANPC1ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924682-B Preparation method of aging-resistant polylactic acid material and aging-resistant polylactic acid material 深圳市久信达科技有限公司 2025-03-25 CN claimed
CN-118459797-A Aging-resistant toughening biodegradable master batch and film, and preparation and application thereof 新疆蓝山屯河科技股份有限公司 2024-08-09 CN claimed
CN-117924682-A Preparation method of aging-resistant polylactic acid material and aging-resistant polylactic acid material 深圳市久信达科技有限公司 2024-04-26 CN claimed
CN-117683240-A Method for preparing iron-based MOFs by electron beam irradiation, iron-based MOFs and application 上海大学 2024-03-12 CN claimed
CN-117343540-A High dielectric constant thermotropic liquid crystal polymer composition and preparation method thereof 宁波聚嘉新材料科技有限公司 2024-01-05 CN claimed
CN-114960229-A Tent cloth dyeing process 圣山集团有限公司 2022-08-30 CN claimed
CN-107910387-A A kind of wide spectrum solar energy materials and preparation method thereof 叶芳 2018-04-13 CN claimed
CN-101309922-A Amino-aza-adamantane derivatives and methods of use ABBOTT LAB (US) 2008-11-19 CN claimed
EP-1926731-A2 AMINO-AZA-ADAMANTANE DERIVATIVES AND METHODS OF USE ABBOTT LABORATORIES (US) 2008-06-04 EP claimed
WO-2007038058-A2 AMINO-AZA-ADAMANTANE DERIVATIVES AND METHODS OF USE ABBOTT LABORATORIES (US) 2007-04-05 WO claimed
US-20070072892-A1 Amino-aza-adamantane derivatives and methods of use ABBOTT LABORATORIES 2007-03-29 US claimed
US-7109243-B2 Inhibitors of cathepsin S IRM LLC (BM) 2006-09-19 US claimed
WO-2026043617-A1 COMPOUNDS AND METHODS OF USE THEREOF FOR TREATMENT OF HEALTH CONDITIONS AND DRUG SCREENING REGLAGENE, INC. (US) 2026-02-26 WO disclosed
CN-120078779-A Composition for inhibiting herpesvirus 威斯康星州医药大学股份有限公司 2025-06-03 CN disclosed
US-20250115608-A1 HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS ARDELYX, INC. (US) 2025-04-10 US disclosed
CN-117924682-B Preparation method of aging-resistant polylactic acid material and aging-resistant polylactic acid material 深圳市久信达科技有限公司 2025-03-25 CN disclosed
US-4505840-A Heterocyclic electroactive polymers CHEVRON RESEARCH COMPANY (US) 1985-03-19 US disclosed
US-4263207-A ANTIALLERGENS MERCK & CO., INC. (US) 1981-04-21 US disclosed
US-4041024-A FOR POLYAMIDES AND POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-09 US disclosed
US-4013632-A SYNTHETIC FIBERS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070072892-A1 Amino-aza-adamantane derivatives and methods of use CHRNA7, CHRNA5, CHRNA1 RAB9A 908/4885NPC1 1243/4885ALDH1A1 1034/4885
US-20250115608-A1 HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS NR1H4, FXR1, GLP1R RAB9A 1557/4885NPC1 1178/4885ALDH1A1 2057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.