Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266093 | 0.85 | ADAMTS5 (0.40) | RAB9ANPC1KDM4ELMNAPOLB | |
| SCHEMBL6265491 | 0.81 | ADAMTS5 (0.45) | RAB9ANPC1KDM4ELMNAMAPT | |
| SCHEMBL6271575 | 0.80 | ADAMTS5 (0.35) | KDM4EMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL6266331 | 0.72 | ADAMTS5 (0.42) | RAB9ANPC1KDM4ECYP1A2MAPT | |
| SCHEMBL6265204 | 0.70 | ADAMTS5 (0.37) | LMNAMAPTL3MBTL1TDP1HTT | |
| SCHEMBL6265252 | 0.69 | ADAMTS5 (0.46) | RAB9ANPC1KDM4ELMNAMAPT | |
| SCHEMBL6276626 | 0.66 | ADAMTS5 (0.51) | RAB9ANPC1LMNAPOLBMAPT | |
| SCHEMBL21664142 | 0.65 | KDM4E (0.43) | RAB9ANPC1KDM4ELMNACCR1 | |
| Dipyridyl SCHEMBL28760321 | 0.61 | KDM4E (0.88) | RAB9ANPC1KDM4ELMNACCR1 | |
| Dipyridyl SCHEMBL27651116 | 0.61 | KDM4E (0.88) | RAB9ANPC1KDM4ELMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | disclosed |