Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266093 | 0.90 | ADAMTS5 (0.40) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6271575 | 0.88 | ADAMTS5 (0.35) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6264285 | 0.83 | ADAMTS5 (0.43) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6264046 | 0.82 | ALDH1A1 (0.41) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6266331 | 0.82 | ADAMTS5 (0.42) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6268159 | 0.81 | RAB9A (0.39) | MAPTKDM4EALDH1A1TDP1GAA | |
| SCHEMBL6262704 | 0.80 | ADAMTS5 (0.49) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6265252 | 0.80 | ADAMTS5 (0.46) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6267527 | 0.79 | ADAMTS5 (0.42) | ADAMTS5MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6267113 | 0.78 | KDM4E (0.41) | ADAMTS5MAPTKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | disclosed |