Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 8/20 | 0.35 |
| ▸ | MECP2 | P51608 | 1/20 | 0.34 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266093 | 0.89 | ADAMTS5 (0.40) | ADAMTS5L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL6265491 | 0.88 | ADAMTS5 (0.45) | ADAMTS5L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL6268159 | 0.80 | RAB9A (0.39) | L3MBTL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6260436 | 0.77 | MECP2 (0.47) | ADAMTS5MECP2MBD2L3MBTL1KDM4E | |
| SCHEMBL6268735 | 0.76 | GCGR (0.39) | ADAMTS5KDM4EALDH1A1GAAMAPT | |
| SCHEMBL6278069 | 0.75 | NPC1 (0.38) | ADAMTS5ALDH1A1CYP19A1 | |
| SCHEMBL6260546 | 0.74 | ADAMTS5 (0.36) | ADAMTS5MECP2MBD2L3MBTL1KDM4E | |
| SCHEMBL6265204 | 0.74 | ADAMTS5 (0.37) | ADAMTS5L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL6271657 | 0.73 | KDM4E (0.44) | ADAMTS5L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL6278562 | 0.73 | ADAMTS5 (0.35) | ADAMTS5MECP2MBD2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092304-A2 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2005-10-06 | — | — | WO | claimed |