SCHEMBL6268909

SCHEMBL6268909

C=CC(Br)(OC(Br)(C=C)c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.37
TSHR P16473 4/20 0.36
ALDH1A1 P00352 4/20 0.36
KCNN4 O15554 4/20 0.36
ALOX15 P16050 1/20 0.34
HTT P42858 1/20 0.34
KIF11 P52732 1/20 0.31
KDM4E B2RXH2 1/20 0.31
AKT1 P31749 1/20 0.30
CYP1A2 P05177 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009599 0.75 ALDH1A1 (0.41) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL60172 0.75 MAPK1 (0.37) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL7123831 0.75 TSHR (0.48) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL11468479 0.74 ALDH1A1 (0.39) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL16933814 0.74 ALDH1A1 (0.39) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL1064377 0.73 TSHR (0.43) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL9774964 0.72 TSHR (0.50) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL8634589 0.71 KCNN4 (0.44) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL7492434 0.71 MAPK1 (0.44) MAPK1TSHRALDH1A1KCNN4ALOX15
SCHEMBL1587335 0.70 ALDH1A1 (0.41) MAPK1TSHRALDH1A1KCNN4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed