Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10608360 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL902761 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL4887210 | 0.77 | KDM4E (0.48) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL6268909 | 0.75 | MAPK1 (0.37) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL16933814 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL11468479 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL3284526 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL11411564 | 0.73 | TSHR (0.46) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL29032839 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4EHTTCYP1A2 | |
| SCHEMBL8854227 | 0.73 | KCNN4 (0.46) | ALDH1A1TSHRKDM4EHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570489-B | Method for preparing cis-olefin from alkyne through copper catalysis | UNIV NORTHWEST A&F | 2015-06-24 | — | — | CN | claimed |
| CN-103570489-A | Method for preparing cis-olefin from alkyne through copper catalysis | UNIV NORTHWEST A&F | 2014-02-12 | — | — | CN | claimed |
| JP-4321689-A | — | — | None | — | — | JP | disclosed |
| CN-114957086-B | Synthesis method and application of N-trifluoromethyl sulfonyl phthalimide | 杭州师范大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114957086-A | Synthesis method and application of N-trifluoromethylsulfonyl phthalimide | 杭州师范大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-103570489-B | Method for preparing cis-olefin from alkyne through copper catalysis | UNIV NORTHWEST A&F | 2015-06-24 | — | — | CN | disclosed |
| CN-103570489-A | Method for preparing cis-olefin from alkyne through copper catalysis | UNIV NORTHWEST A&F | 2014-02-12 | — | — | CN | disclosed |
| US-5550248-A | Substituted stryl heterocyclic amido prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0447188-B1 | 7-Oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic diseases | SQUIBB & SONS INC (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0391652-B1 | Interphenylène 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease | SQUIBB & SONS INC (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5290799-A | 7-oxabicycloheptyl substituted heterocyclic thioamide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5100889-A | Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0476994-A1 | 7-Oxabicycloheptyl substituted heterocyclic thioamide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E.R. SQUIBB & SONS, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0447188-A2 | 7-Oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4977174-A | Anticoagulants, antischemic agents | E. R. SQUIBB & SONS, INC. (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0391652-A1 | Interphenylène 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease | E.R. SQUIBB & SONS, INC. (US) | 1990-10-10 | — | — | EP | disclosed |
| EP-0369279-A1 | 7-oxabicycloheptane imino interphenyleneoxy substituted prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E.R. SQUIBB & SONS, INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0369278-A1 | 7-oxabicycloheptane imino interphenylene substituted prostaglandin analogs useful in the treatment of thrombotic disease | E.R. SQUIBB & SONS, INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4883811-A | 7-Oxabicycloheptane imino interphenylene substituted prostaglandin analogs useful in the treatment of thrombotic disease | E. R. SQUIBB & SONS, INC. | 1989-11-28 | — | — | US | disclosed |
| US-4883809-A | 7-Oxabicycloheptane imino interphenyleneoxy substituted prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. | 1989-11-28 | — | — | US | disclosed |