Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.44 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.44 |
| ▸ | GGH | Q92820 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626934 | 1.00 | FOLH1 (0.44) | FOLH1NAALAD2RIMKLAGGHFNTA | |
| SCHEMBL28165029 | 0.87 | MEN1 (0.37) | FOLH1NAALAD2RIMKLAGGHMEN1 | |
| SCHEMBL18248134 | 0.87 | CTSK (0.46) | MEN1GAAKMT2A | |
| SCHEMBL7898369 | 0.84 | MEN1 (0.37) | MEN1GAAKMT2A | |
| SCHEMBL8751934 | 0.83 | CYP2D6 (0.36) | FNTAFNTBMEN1GAAKMT2A | |
| SCHEMBL8751927 | 0.83 | CYP2D6 (0.36) | FNTAFNTBMEN1GAAKMT2A | |
| SCHEMBL5961042 | 0.82 | GABRP (0.37) | MEN1GAAKMT2A | |
| SCHEMBL4971083 | 0.81 | CTSK (0.42) | MEN1GAAKMT2A | |
| SCHEMBL4096308 | 0.81 | CTSK (0.42) | MEN1GAAKMT2A | |
| SCHEMBL1162877 | 0.81 | CTSK (0.42) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601519-A | Loadable porous structures for use as implants | 泰坦医药品公司 | 2021-04-02 | — | — | CN | claimed |
| CN-118680883-A | Loadable porous structure for use as an implant | 瑞艾克斯制药公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-118055760-A | Implantable reservoirs with adjustable release profile | 铸造疗法股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-116650732-A | Devices, systems, and methods for treating intracavity cancers via controlled delivery of therapeutic agents | 铸造疗法股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-111787971-B | Device for rectal anesthesia | 新梅迪克设备有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-109125814-B | Anti-adhesion membrane and preparation method thereof | 上海微创医疗器械（集团）有限公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-113181439-A | Multilayer polymer film | 胡姬医疗科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-112601519-A | Loadable porous structures for use as implants | 泰坦医药品公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-112367980-A | Implantable reservoir for controlled release of therapeutic agents | 铸造疗法股份有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-111787971-A | Method and device for rectal anesthesia | 新梅迪克设备有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-111432807-A | Implantable reservoir for controlled release of therapeutic agents | 铸造疗法股份有限公司 | 2020-07-17 | — | — | CN | disclosed |
| EP-3630269-A1 | DEVICE FOR INSERTION INTO NERVOUS TISSUE | Neuronano AB (SE) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018217147-A1 | DEVICE FOR INSERTION INTO NERVOUS TISSUE | NEURONANO AB (SE) | 2018-11-29 | — | — | WO | disclosed |
| EP-2603238-B1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AN OCULAR DISEASE IN A SUBJECT | INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) | 2014-07-30 | — | — | EP | disclosed |
| US-20130261535-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AN OCULAR DISEASE IN A SUBJECT | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2013-10-03 | — | — | US | disclosed |
| EP-2603238-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AN OCULAR DISEASE IN A SUBJECT | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2013-06-19 | — | — | EP | disclosed |
| US-8454937-B2 | microbubbles comprising gases and DNA viruses comprising an expression cassette that code for green fluorescent protein, luciferase, chloramphenicol transferase, beta -glucuronidase or beta -galactosidase, encapsulated in protein or phosphatide shells; drug delivery; tissue-targeted therapy | Temple University—Of The Commonwealth System of High Education (US) | 2013-06-04 | — | — | US | disclosed |
| WO-2012020001-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AN OCULAR DISEASE IN A SUBJECT | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2012-02-16 | — | — | WO | disclosed |
| US-20080063604-A1 | Method and composition for the site-selective gene delivery using viruses | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2008-03-13 | — | — | US | disclosed |