Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5922114 | 1.00 | PKM (0.50) | PKMALDH1A1POLBMAPK1ATM | |
| SCHEMBL9638084 | 0.98 | PKM (0.49) | PKMALDH1A1POLBMAPK1ATM | |
| SCHEMBL875653 | 0.86 | ALDH1A1 (0.62) | PKMALDH1A1POLBMAPK1ATM | |
| SCHEMBL5702742 | 0.86 | ALDH1A1 (0.62) | PKMALDH1A1POLBMAPK1ATM | |
| SCHEMBL8423882 | 0.81 | HDAC6 (0.36) | ALDH1A1HSD17B10LMNAGAAHCAR3 | |
| SCHEMBL6269796 | 0.79 | ALDH1A1 (0.36) | PKMALDH1A1POLBMAPK1ATM | |
| SCHEMBL27479833 | 0.78 | HCAR3 (0.58) | POLBHCAR3 | |
| SCHEMBL10422321 | 0.75 | HCAR3 (0.44) | POLBHCAR3 | |
| SCHEMBL11077694 | 0.75 | POLB (0.60) | ALDH1A1POLBMAPK1ATMHSD17B10 | |
| SCHEMBL16863946 | 0.72 | PKM (0.58) | PKMALDH1A1POLBMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606447-A1 | OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE | Lanxess B.V. (NL) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004083516-A1 | OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE | LANXESS B.V. (NL) | 2004-09-30 | — | — | WO | disclosed |