SCHEMBL6270102

SCHEMBL6270102

ON=C1c2ccccc2Cc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
ALDH1A1 P00352 3/20 0.53
CYP1A2 P05177 3/20 0.53
CYP2C19 P33261 1/20 0.53
MAOA P21397 1/20 0.50
CDK5 Q00535 3/20 0.45
CDK5R1 Q15078 2/20 0.45
HPGD P15428 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
BCHE P06276 1/20 0.41
CES1 P23141 1/20 0.41
SRD5A2 P31213 1/20 0.41
RNASEH1 O60930 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7945985 0.86 KMT2A (0.61) MEN1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL11317004 0.86 ALDH1A1 (0.59) MEN1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL11317002 0.86 ALDH1A1 (0.59) MEN1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL11838507 0.82 HPGD (0.62) MEN1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL29493736 0.79 KMT2A (0.94) MEN1KMT2AALDH1A1CYP1A2CYP2C19
Fluorene SCHEMBL30173241 0.79 MAOA (0.65) MEN1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL3401938 0.79 KMT2A (0.94) MEN1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL14520877 0.77 ALDH1A1 (0.66) MEN1KMT2AALDH1A1CYP1A2CYP2C19
Fluorene SCHEMBL30898827 0.76 MAOA (0.62) MEN1KMT2AALDH1A1CYP1A2CYP2C19
SCHEMBL29941712 0.76 KMT2A (1.00) MEN1KMT2AALDH1A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462542-A Cyanuric chloride oxime ester and synthesis method thereof 九江善水科技股份有限公司 2025-02-18 CN disclosed
US-9411226-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-09 US disclosed
US-9411226-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-09 US disclosed
US-7807841-B2 Spiro-containing compounds and compositions as modulators of steroid hormone nuclear receptors IRM LLC (BM) 2010-10-05 US disclosed
US-20090124597-A1 SPIRO-CONTAINING COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS IRM LLC (BM) 2009-05-14 US disclosed
EP-1137703-B1 STABILIZED THERMOPLASTIC COMPOSITIONS CROMPTON CORP (US) 2005-12-28 EP disclosed
EP-1137703-A1 STABILIZED THERMOPLASTIC COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2001-10-04 EP disclosed
US-6214915-B1 AROMATIC KETONE STABILIZER GENERAL ELECTRIC COMPANY 2001-04-10 US disclosed
WO-2000034373-A1 STABILIZED THERMOPLASTIC COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2000-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124597-A1 SPIRO-CONTAINING COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS NR3C2, NR5A1, ESRRA MEN1 1744/4885KMT2A 3845/4885ALDH1A1 1202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.