Fluorene

Fluorene

SCHEMBL30173241

[N].c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.65
KDM4E B2RXH2 2/20 0.58
NPC1 O15118 2/20 0.58
MAPT P10636 2/20 0.58
RAB9A P51151 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
CES1 P23141 2/20 0.52
BCHE P06276 1/20 0.52
SRD5A2 P31213 1/20 0.50
PLK4 O00444 1/20 0.48
DAPK3 O43293 1/20 0.48
PIM1 P11309 1/20 0.48
PDGFRA P16234 1/20 0.48
LTK P29376 1/20 0.48
MAP2K2 P36507 1/20 0.48
FLT3 P36888 1/20 0.48
MAPK8 P45983 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL29767424 0.97 MAOA (0.62) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL30898827 0.97 MAOA (0.62) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29355380 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29478468 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL8180 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL545861 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL31388525 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL9435671 0.93 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL9791437 0.93 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL6739194 0.93 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119771366-A Nitrogen-rich porous polymer adsorbent containing rigid fluorene structure, and preparation method and application thereof 常州大学 2025-04-08 CN disclosed
CN-114989399-B Room temperature Suzuki cross-coupling polymerization method of conjugated polymer semiconductor material 中国科学院大学 2023-08-01 CN disclosed
WO-2023013575-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2023-02-09 WO disclosed