Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280509 | 0.84 | NPC1 (0.51) | LMNAALDH1A1TSHRCYP3A4NPC1 | |
| SCHEMBL5149165 | 0.81 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRMMP8KMT2A | |
| SCHEMBL28647877 | 0.81 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRMMP8KMT2A | |
| SCHEMBL1144506 | 0.81 | KMT2A (0.52) | LMNAALDH1A1TSHRMMP8KMT2A | |
| SCHEMBL1144389 | 0.81 | KMT2A (0.52) | LMNAALDH1A1TSHRMMP8KMT2A | |
| SCHEMBL1405716 | 0.81 | KMT2A (0.52) | LMNAALDH1A1TSHRMMP8KMT2A | |
| SCHEMBL8121589 | 0.81 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRMMP8KMT2A | |
| SCHEMBL14630051 | 0.80 | SMN1; SMN2 (0.49) | LMNAALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL16268748 | 0.79 | LMNA (0.51) | LMNAALDH1A1TSHRMMP8MDM4 | |
| SCHEMBL4800772 | 0.79 | EEF2K (0.47) | ALDH1A1KMT2AMEN1MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095325-A1 | PROCESS FOR THE PREPARATION OF β-AMINOCARBOXYLIC ACIDS | DEGUSSA AG (DE) | 2005-10-13 | — | — | WO | disclosed |