Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 3/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693226 | 0.86 | CYP2C19 (0.45) | GABBR2GABBR1ALDH1A1EPHX1CYP2C19 | |
| SCHEMBL13140927 | 0.81 | RIPK1 (0.46) | L3MBTL1EPHX1CYP2C19CYP2D6MEN1 | |
| SCHEMBL12572468 | 0.81 | RIPK1 (0.46) | L3MBTL1EPHX1CYP2C19CYP2D6MEN1 | |
| SCHEMBL4574137 | 0.81 | RIPK1 (0.46) | L3MBTL1EPHX1CYP2C19CYP2D6MEN1 | |
| SCHEMBL26228615 | 0.80 | L3MBTL1 (0.51) | L3MBTL1CYP2C19CTSASMN1; SMN2MAPT | |
| SCHEMBL6270165 | 0.79 | LMNA (0.46) | ALDH1A1CYP2C19CYP2D6SMN1; SMN2MAPT | |
| SCHEMBL8332653 | 0.79 | EEF2K (0.50) | EEF2KGABBR2GABBR1ATML3MBTL1 | |
| SCHEMBL1144429 | 0.77 | ALDH1A1 (0.59) | EEF2KGABBR2GABBR1ATML3MBTL1 | |
| SCHEMBL2300538 | 0.77 | ALDH1A1 (0.59) | EEF2KGABBR2GABBR1ATML3MBTL1 | |
| SCHEMBL4944942 | 0.77 | GABBR2 (0.53) | EEF2KGABBR2GABBR1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. | 2015-12-10 | — | — | US | disclosed |
| EP-1988078-B1 | Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine for the treatment of thrombosis disorders | ORTHO MCNEIL PHARM INC (US) | 2012-10-17 | — | — | EP | disclosed |
| US-7385080-B2 | Method for producing optically active β-phenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2008-06-10 | — | — | US | disclosed |
| EP-1141333-B1 | PROCESS FOR THE ENZYMATIC PREPARATION OF AMINO ACID DERIVATIVES WITH ENHANCED OPTICAL PURITY | DSM IP ASSETS BV (NL) | 2006-06-14 | — | — | EP | disclosed |
| US-20050065366-A1 | Method for producing optically active beta-phenylalanine compounds | AJINOMOTO CO., INC. (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1484314-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE BETA-PHENYLALANINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2004-12-08 | — | — | EP | disclosed |
| EP-1349857-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055521-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |
| EP-1013769-A1 | Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity | DSM N.V. (NL) | 2000-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | EEF2K 1613/4885GABBR2 4193/4885GABBR1 3837/4885 |
| US-20050065366-A1 | Method for producing optically active beta-phenylalanine compounds | PAH, NPEPPS, DNPEP | EEF2K 559/4885GABBR2 1275/4885GABBR1 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.