Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274464 | 0.89 | HTR6 (0.46) | HTR6HPGDLMNAPDE4APDE4B | |
| SCHEMBL6273306 | 0.88 | HTR6 (0.45) | HTR6HPGDLMNAFFAR4ALDH1A1 | |
| SCHEMBL6271452 | 0.87 | CA12 (0.50) | ALDH1A1NPSR1GAA | |
| SCHEMBL6271259 | 0.85 | HTR6 (0.43) | HTR6HPGDLMNAPDE4APDE4B | |
| SCHEMBL6269080 | 0.85 | HTR6 (0.50) | HTR6HPGDLMNAPDE4APDE4B | |
| SCHEMBL6273783 | 0.77 | SMN1; SMN2 (0.52) | LMNAALDH1A1KDM4ENPSR1GAA | |
| SCHEMBL6272488 | 0.77 | F2 (0.37) | FFAR4 | |
| SCHEMBL6272642 | 0.76 | SMN1; SMN2 (0.43) | HPGDLMNAPDE4APDE4BPDE4C | |
| SCHEMBL6272920 | 0.76 | CA12 (0.48) | LMNAALDH1A1NPSR1GAA | |
| SCHEMBL6271776 | 0.76 | FFAR4 (0.35) | L3MBTL1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |