Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270628 | 0.89 | HTR6 (0.47) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6273783 | 0.88 | SMN1; SMN2 (0.52) | LMNAKMT2A | |
| SCHEMBL6273306 | 0.87 | HTR6 (0.45) | HTR6LMNAHPGDFFAR4KMT2A | |
| SCHEMBL6272642 | 0.87 | SMN1; SMN2 (0.43) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL6269080 | 0.86 | HTR6 (0.50) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6271259 | 0.82 | HTR6 (0.43) | HTR6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6271452 | 0.77 | CA12 (0.50) | KMT2A | |
| SCHEMBL9756722 | 0.77 | LMNA (0.52) | LMNAHPGDMAPTFFAR4KMT2A | |
| SCHEMBL6272920 | 0.76 | CA12 (0.48) | LMNAKMT2A | |
| SCHEMBL6275310 | 0.75 | L3MBTL1 (0.37) | PDE4APDE4BPDE4CPDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |