SCHEMBL6270684

SCHEMBL6270684

CCN1C(=O)c2cccc3cccc1c23

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
HPGD P15428 2/20 1.00
CASP1 P29466 1/20 1.00
MPI P34949 1/20 1.00
CACNA1B Q00975 1/20 1.00
APBA1 Q02410 1/20 1.00
CYP1B1 Q16678 3/20 0.77
L3MBTL1 Q9Y468 3/20 0.66
KDM4E B2RXH2 2/20 0.61
POLB P06746 1/20 0.61
MAPT P10636 2/20 0.61
MEN1 O00255 1/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 1/20 0.61
APAF1 O14727 1/20 0.60
GAA P10253 1/20 0.60
THRB P10828 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
UBE2N P61088 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437299 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL117049 0.87 CYP1B1 (1.00) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL7131251 0.83 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL9720971 0.82 HPGD (0.70) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL7130039 0.81 HPGD (0.69) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL9720875 0.81 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL9720969 0.80 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL11211234 0.80 HPGD (0.66) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL7071975 0.79 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2HPGDCASP1MPI
SCHEMBL9290383 0.79 HEXA (0.78) ALDH1A1SMN1; SMN2HPGDCASP1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION REVVITY HEALTH SCIENCES, INC. 2023-05-25 US disclosed
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION REVVITY HEALTH SCIENCES, INC. 2023-05-25 US disclosed
US-11549017-B2 NIR to SWIR fluorescent compounds for imaging and detection PERKINELMER HEALTH SCIENCES, INC. (US) 2023-01-10 US disclosed
CN-111662226-B 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound 中国科学院广州生物医药与健康研究院 2022-03-18 CN disclosed
US-20210130581-A1 NEAR INFRARED (NIR) LASER PROCESSING OF RESIN BASED ARTICLES AGFA-GEVAERT NV (BE) 2021-05-06 US disclosed
US-20210016588-A1 NEAR INFRARED (NIR) LASER PROCESSING AGFA-GEVAERT NV (BE) 2021-01-21 US disclosed
CN-105985282-B 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound and application thereof 中国科学院广州生物医药与健康研究院 2020-12-08 CN disclosed
CN-111662226-A 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound 中国科学院广州生物医药与健康研究院 2020-09-15 CN disclosed
US-20200148907-A1 NEAR INFRARED (NIR) LASER MARKABLE COMPOSITIONS AGFA NV (BE) 2020-05-14 US disclosed
WO-2019110438-A1 NEAR INFRARED (NIR) LASER PROCESSING AGFA NV (BE) 2019-06-13 WO disclosed
EP-0050263-B1 CATIONIC DYES, THEIR PREPARATION AND THEIR USE IN THE DYEING OF CATIONICALLY DYEABLE FIBRES AND PAPER BAYER AG (DE) 1983-08-03 EP disclosed
EP-0081125-A1 Cationic dyes, their preparation process and their use in dyeing and mass dyeing BAYER AG (DE) 1983-06-15 EP disclosed
US-4332937-A DYES FOR POLYACRYLONITRILE CIBA-GEIGY CORPORATION (US) 1982-06-01 US disclosed
EP-0050263-A1 Cationic dyes, their preparation and their use in the dyeing of cationically dyeable fibres and paper BAYER AG (DE) 1982-04-28 EP disclosed
US-4283540-A ETHERIFICATION OF A CATIONIC DYE WITH A POLYHYDRIC ALCOHOL BAYER AKTIENGESELLSCHAFT (DE) 1981-08-11 US disclosed
US-4185151-A 1-R-2-(U-HYDROXYALKYL-2,2,4-TRIMETHYL TETRAHYDROQUINOL-6-YL) BENZ(CD)INDOLES BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-RE29834-E PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS BAYER AKTIENGESELLSCHAFT (DE) 1978-11-14 US disclosed
US-4080331-A 2-DICYANOMETHYLENE BENZINDOLE DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1978-03-21 US disclosed
US-3971807-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3959310-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11549017-B2 NIR to SWIR fluorescent compounds for imaging and detection SMARCD1, SMARCE1, SMARCB1 ALDH1A1 3287/4885SMN1; SMN2 1516/4885HPGD 2747/4885
US-20230159762-A1 NIR TO SWIR FLUORESCENT COMPOUNDS FOR IMAGING AND DETECTION SMARCD1, SMARCE1, SMARCB1 ALDH1A1 3287/4885SMN1; SMN2 1516/4885HPGD 2747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.