Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | MPI | P34949 | 1/20 | 0.66 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.66 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.63 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.63 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | HEXA | P06865 | 1/20 | 0.58 |
| ▸ | HEXB | P07686 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377100 | 0.92 | ALDH1A1 (0.62) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL6263721 | 0.90 | POLB (0.76) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL8396166 | 0.83 | LCK (0.73) | ALDH1A1POLBMEN1CYP1A2TNNI3 | |
| SCHEMBL9720920 | 0.83 | POLB (0.47) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL1569105 | 0.81 | POLB (0.74) | ALDH1A1HPGDSMN1; SMN2POLBMEN1 | |
| SCHEMBL7131251 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL9720971 | 0.80 | HPGD (0.70) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL6270684 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL29437299 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL30272534 | 0.80 | TERT (0.59) | ALDH1A1HPGDCASP1MPICACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |