Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267075 | 0.82 | KMT2A (0.53) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6268955 | 0.81 | MEN1 (0.53) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6274074 | 0.80 | GAA (0.45) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6267894 | 0.80 | KMT2A (0.51) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6272969 | 0.78 | MEN1 (0.48) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6332076 | 0.78 | CA12 (0.56) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6274189 | 0.77 | MEN1 (0.48) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6270007 | 0.77 | MEN1 (0.48) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL3148800 | 0.77 | L3MBTL1 (0.56) | LMNAMAPK1RAB9AMEN1KMT2A | |
| SCHEMBL6274191 | 0.76 | MEN1 (0.49) | LMNAMAPK1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |