Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267075 | 0.82 | KMT2A (0.53) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6267894 | 0.80 | KMT2A (0.51) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6332076 | 0.80 | CA12 (0.56) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6275296 | 0.79 | ADRB2 (0.44) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6275292 | 0.79 | ADRB2 (0.44) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6274320 | 0.77 | KMT2A (0.46) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6274189 | 0.77 | MEN1 (0.48) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6272861 | 0.76 | MEN1 (0.44) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6271745 | 0.76 | LMNA (0.53) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6268955 | 0.75 | MEN1 (0.53) | MEN1KMT2ALMNAMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |