Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271745 | 0.80 | LMNA (0.53) | GAANPSR1ALDH1A1KDM4ELMNA | |
| SCHEMBL6267973 | 0.76 | GAA (0.41) | GAAALDH1A1KDM4EHSD17B10CA12 | |
| SCHEMBL6677922 | 0.74 | CA2 (0.49) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| Hydrochloric Acid SCHEMBL6800403 | 0.73 | CA2 (0.48) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL19332547 | 0.72 | GAA (0.47) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27513611 | 0.72 | CYP1A2 (0.62) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3057899 | 0.72 | ALDH1A1 (0.49) | GAAALDH1A1KDM4EHSD17B10CYP1A2 | |
| SCHEMBL2665963 | 0.72 | LMNA (0.56) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2665972 | 0.72 | KMT2A (0.57) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL68851 | 0.72 | CYP4Z1 (0.62) | GAAALDH1A1KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |